Audio Settings

Be sure that your audio settings are correctly configured. If you're not sure about the optimal settings, try to replicate these:

  • Audio Device Type (Windows Only): ASIO
  • Audio Input Device: (This will vary depending on your audio interface)
  • Audio Output Device: (Select the same device as above)
  • Audio Output Channels: L and R or 1 and 2
  • Audio Input Channels: Input 1 or 2 (Disable all the inputs you're not using)
  • Sample Rate: 44100 Hz
  • Buffer Size: 128 or 256 Samples

Other things you can check:

  • Check the ground connection of your guitar, this is extremely important. It can reduce your noise a lot! Good pickups too!
  • Use a short and good quality guitar/instrument cable.
  • Be sure your screen is not causing the extra noise, by interfering with your pickups. Take the guitar to face a different direction and check. 
  • Check if your position in the room with your instrument affects the level of the noise (really!)
  • Borrow or buy a DI box, so you can go with a Balanced signal into your interface, this will for sure reduce the noise too.
  • Use MONO input configuration with the plugin.

Please, make sure the input configuration is set to MONO. Maybe, If it is a stereo input, there is a chance the second channel is introducing noise

Make sure your bit depth and buffer size are correctly in your audio settings.

Well, some models have LOTS OF GAIN, especially with the overdrive pedal ON. They will get very noisy with too much boost since your noise floor is raised. 

Also, spread the mics towards the corners of the speakers will reduce high frequencies, like a low shelf pass filter. I.E., "Ribbon" and "Dynamic" are great mics to get warmer tones.

If you’re unable to clean your signal, check the following links to get some ideas on how to mitigate the issue: 

1) Clean Up a noisy signal

2) Solving Noise, Hum & Buzz.